TY - BOOK AU - Samir Ahmed Shawky AU - Abeer Ahmad Bahnassy , AU - Hussein Mostafa Khaled , AU - Mohamed Halmy Elborai , TI - DNA methylation status of dapk and MT1G genes in diffuse large B-cell lympihoma and its clinical relevance / PY - 2012/// CY - Cairo : PB - Samir Ahmed Shawky , KW - DAPK KW - MT1G KW - Promotor hypermethylation N1 - This thesis arrived by email without CD; Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology-Pathology N2 - Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of of Non-hodgkin's lymphoma (NHL) and can be divided into prognostically important subgroups with germinal center B-cell-like (GCB) and non-GCB subtypes either by using cDNA microarray or immunostains (CD10, BCL6, MUM1). Beyond genetic alterations, identification of novel epigenetic alterations, such as aberrant methylation may yield better diagnostic, prognostic and therapeutic information ER -