Hairy cell leukemia management and outcome with cladribine (2- chlorodeoxyadenosine) treatment activity and toxicity /
العلاج بعقار الكلادريبين ونتائجه فى مرضى سرطان الدم ذو الخلية المشعرة نتائج العلاج والأعراض الجانبية
Tarek Yakout Mohamed ; Supervised Ola Mohamed Reda Khorshid , Alfred Elias Namour , Mosaad Mahmoud Elgammal
- Cairo : Tarek Yakout Mohamed , 2013
- 98 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology (Medical)
Hairy cell leukemia (HCL) is rare B- cell lymphoproliferative disorder . Its treatment has evolved from splenectomy with time to failure (TTF) of 19 months to cladribine that increased complete remission (CR) rate to 90% with only small percentage of patients relapsing at 30 months . Cladribine (CDA) is originally administered intravenously as continuous infusion for 7 days