TY - BOOK AU - Noura Ibrahium Abdelrazek Mourad AU - Dalia Roshd Ahmed Abdelrahman , AU - Mennat Allah Kamal Eldin , AU - Mohamed Nagib Abdallah Shaaban , TI - Trial to determine the optimal dose of recombinant hirudin in hemodialysis patients / PY - 2013/// CY - Cairo : PB - Noura Ibrahium Abdelrazek Mourad , KW - Blood urea nitrogen KW - Chronic kidney disease KW - Hemodialysis N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine; Issued also as CD N2 - Heparins are currently the anticoagulants of choice in long- term hemodialysis (HD) . Because of their shortcomings including the increasing incidence of heparin - induced thrombocytopenia (HIT {u2161} ) Osteoprosis, skin necrosis, hypersensitivity and hypoaldosteronism alternative anticoagulant is necessary ER -