TY  - BOOK
AU  - Amro Hefnawy Mohamed Hefnawy
AU  - Ashraf Mustafa Kamal Hassan Abadi , 
TI  - Modulating celecoxib activity towards phosphodiesterase 5 inhibition rather than cyclooxygenase inhibition and evaluating its correlation to anticancer activity / 
PY  - 2013///
CY  - Cairo : 
PB  - Amro Hefnawy Mohamed Hefnawy , 
N1  - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
N2  - Selective COX-2 inhibitors were introduced as safer alternatives to NSAIDs with less gastrointestinal side effects. Celecoxib, Rofecoxib and valdecoxib were the most widely used COX-2 inhibitors. Unfortunately, it was found that the use of selective COX-2 inhibitors is associated with increased cardiovascular risk. By 2011, celecoxib was the only selective COX-2 inhibitors to remain available in the market as it showed better cardiovascular safety
UR  - http://172.23.153.220/th.pdf
ER  -