TY  - BOOK
AU  - Aya Zakaria Gamal Eldin Rashed
AU  - Nabila Hamdi , 
AU  - Reham Mahmoud Abdelkader , 
TI  - Methylene blue decreases brain mitochondrial ABAD levels protecting mitochondrial function / 
PY  - 2013///
CY  - Cairo : 
PB  - Aya Zakaria Gamal Eldin Rashed , 
N1  - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology
N2  - Methylene blue (MB) is lately being proposed to be effective in treating alzheimer's disease (AD). Phase 2 clinical trials reported improvements in cognitive functions of AD patients after MB treatment. However, the exact mechanism of action of MB is still controversial and needs further investigations. Recently, the mitochondrial enzyme amyloid binding alcohol dehydrogenase (ABAD) has been shown to bind AÝ inducing mitochondrial dysfunction, providing a direct relation between AÝ and mitochondrial dysfunction occurring in AD
UR  - http://172.23.153.220/th.pdf
ER  -