Radwa Abdelmoniem Mohamed Ahmed <br/><br/>
Formulation and evaluation of metochlopromide - loaded solid lipid nanoparticles for rectal delivery /  
 تركيب و تقييم الجزيئات المتناهية الصغر المحملة بالميتوكلوبراميد للتوصيل الشرجى 
Radwa Abdelmoniem Mohamed Ahmed ; Supervised Haidy Atef Abass , Mohamed Ali Attia Shafie 
 - Cairo :   Radwa Abdelmoniem Mohamed Ahmed ,   2012 
 - 92 Leaves :   charts ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology 
<br/><br/> Solid lipid nanoparticles technology represents a promising new approach for lipophilic drug delivery. Solid lipid nanoparticles were introduced at the beginning of 1990s as an alternative to emulsions and liposomes in cosmetic and pharmaceutical preparations. The objective of present study was to develop solid lipid nanoparticle containing metoclopramide by a novel method using high shear homogenization (hot homogenization) technique then incorporating them into suppository for treatment of nausea and vomiting