TY - BOOK AU - Radwa Abdelmoniem Mohamed Ahmed AU - Haidy Atef Abass , AU - Mohamed Ali Attia Shafie , TI - Formulation and evaluation of metochlopromide - loaded solid lipid nanoparticles for rectal delivery / PY - 2012/// CY - Cairo : PB - Radwa Abdelmoniem Mohamed Ahmed , N1 - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology N2 - Solid lipid nanoparticles technology represents a promising new approach for lipophilic drug delivery. Solid lipid nanoparticles were introduced at the beginning of 1990s as an alternative to emulsions and liposomes in cosmetic and pharmaceutical preparations. The objective of present study was to develop solid lipid nanoparticle containing metoclopramide by a novel method using high shear homogenization (hot homogenization) technique then incorporating them into suppository for treatment of nausea and vomiting UR - http://172.23.153.220/th.pdf ER -