TY - BOOK AU - Mona Aly Elkhatieb AU - Hans Georg Breitinger , AU - Walter StÜhmer , TI - Discovery of novel inhibitors of the cancer related voltage - gated potassium channel Kv10.1 from marine sources / PY - 2013/// CY - Cairo : PB - Mona Aly Elkhatieb , N1 - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Biochemistry N2 - Cancer is a leading cause of morbidity worldwide. In the US, it is the second most frequent cause of death after cardiovascular diseases. According to the American cancer society, the annual total costs of cancer in 2008 were $ 201.5 billion. The treatment regimen usually includes chemotherapy, which itself represents a part of the problem. Most chemotherapeutic drugs are cytotoxic to both cancer and healthy cells, and thus cause severe side effects ER -