TY  - BOOK
AU  - Aya Magdi Ibrahim Alorbani
AU  - Hoda Mohamed Hussein Rasheed , 
AU  - Mohamed Hussein Medhat Elkomy , 
AU  - Olfat Gamil Shaker , 
TI  - Expression of sirtuin 1 and its relation to tumor necrosis factor - alpha in psoriatic plaques / 
PY  - 2014///
CY  - Cairo : 
PB  - Aya Magdi Ibrahim Alorbani , 
KW  - Psoriasis
KW  - Sirtuins
KW  - Tumor necrosis factor
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology; Issued also as CD
N2  - Although it is now considered a prototypic Th1/Th17-mediated disease, several gaps still exist in our understanding of the pathogenesis of psoriasis. Sirtuins, a family of seven proteins that have generated huge interest in several fields including dermatology, have been proposed to contribute to the development of inflammatory and hyperproliferative disease. It has been proposed that changes in Sirtuin 1 (SIRT1), through its effect on pro-inflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-Ü), may contribute to the development of the psoriatic plaque
UR  - http://172.23.153.220/th.pdf
ER  -