TY  - BOOK
AU  - Doaa Ibrahim Mohammed Elsayed
AU  - Akmal Abdelreheim Elghor , 
AU  - Nahed Ahmed Hussien Ahmed , 
AU  - Nahla Gamal Eldin Mohamed , 
TI  - Antiproliferative and apoptotic effects of grape seed extract on human colon cancer cell line HCT116 / 
PY  - 2013///
CY  - Cairo : 
PB  - Doaa Ibrahim Mohammed Elsayed , 
KW  - Colorectal cancer
KW  - HCT116
KW  - WISH
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology; Issued also as CD
N2  - Grape seed extract (GSE) has been proven to inhibit cell proliferation and induce apoptosis in various human carcinoma cell lines. Herein, we evaluated the in vitro antiproliferative and apoptotic effects of GSE against colon cancer cell line HCT116. The cytotoxic effect of GSE was examined on human colon cancer HCT116 and normal WISH cells. In addition, we evaluated the antiproliferative and apoptotic effects of different concentrations of GSE (25, 50 and 100 æg / ml) at different sampling time (24, 48, 72 and 96hrs) on HCT116 cells using cell proliferation and DNA fragmentation assays respectively
ER  -