TY - BOOK AU - Labib Abbas Hafez AU - Eman Medhat Hassan , AU - Mohammad Salah Abdelbary , AU - Olfat Gamil Shaker , TI - Serum and Biliary Insulin-like Growth Factor I As A Diagnostic Marker for Cholangiocarcinoma / PY - 2013/// CY - Cairo : PB - Labib Abbas Hafez , KW - Cholangiocarcinoma KW - Insulin-like growth factor I KW - Pancreatic cancer N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine; Issued also as CD N2 - Background: Cholangiocarcinoma (CCA) is the most frequent biliary malignancy. It is difficult to diagnose owing to its anatomic location, growth patterns and lack of definite diagnostic criteria. Its cells express and secrete Insulin-like growth factor I (IGF-I). Objective: Measurement of IGF-I in bile and serum of patients with extrahepatic CCA and its evaluation as a diagnostic marker. Methods: The study is a cross sectional study including 60 patients presented to endoscopic retrograde cholangiopancreatography (ERCP) unit for extrahepatic bilairy obstruction. Patients were grouped as follows: Group A including 20 patients with extrahepatic CCA, Group B 20 patients with pancreatic cancer and Group C 20 patients with benign biliary lesions UR - http://172.23.153.220/th.pdf ER -