Interleukin - 10 gene polymorphisms in type - 2 diabetic patients with nephropathy /
التحور الجينى للانترلوكين - 10 في مرضي الاعتلال الكلوى الناتج عن النوع الثانى للبوال السكرى
Engy Medhat Ahmed Abdelmegeed ; Supervised Samia Mostafa Mohamed , Manal Nabih Eldeeb , Nermeen Mohamed Hassan
- Cairo : Engy Medhat Ahmed Abdelmegeed , 2013
- 108 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
Diabetic nephropathy is the most prevalent cause for end - stage renal disease in the united states and the western world. In this disease, tubular injury and progressive interstitial fibrosis contribute significantly to renal failure and predict progression to end-stage renal disease. In early diabetic renal injury, there is podocyte drop - out which is thought to cause glomerular proteinuria and subsequent diabetic glomerular injury. Different inflammatory molecules including pro - inflammatory cytokines have been proposed as critical factors in the development of microvascular diabetic complications including nephropathy
Diabetic nephropathy Interleukin - 10 Type 2 diabetes