Mohamed Fathy Abdelzaher Aly <br/><br/>
Use of real-time three dimensional echocardiography with semi-automatic endocardial contour detection for prediction of response to cardiac resynchronization therapy in patients with heart failure /  
 استخدام الموجات الصوتية ثلاثية الأبعاد بالزمن الحقيقي على القلب بالترافق مع ايجاد الشِبه أوتوماتيكي لحدود الشغاف للتنبؤ بمدى استجابة مرضى قصور القلب عادة ضبط التناسق البطيني 
Mohamed Fathy Abdelzaher Aly ; Supervised Khaled Aly Hassan Sorour , Hossam Ibraheem Kandil , Yasser Ahmed Abdelhady 
 - Cairo :   Mohamed Fathy Abdelzaher Aly ,   2014 
 - 102 P. :   facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology 
<br/><br/> Background: Cardiac resynchronization therapy (CRT) is an established therapy in heart failure. However, one third of patients are non-responders, accordingly, proper selection of CRT eligible patients are essential. Aims: 1) To test their ability to predict response to CRT in patients with ischemic and non-ischemic cardiomyopathy. 2) To compare TomTec and QLAB software packages for the three-dimensional echocardiographic (3DE) assessment of left ventricular (LV) dyssynchrony.  Methods and results: A total of 140 heart failure patients with the LVEF 35% and 60 healthy volunteers underwent 3DE. A subgroup of 60 patients underwent CRT and were evaluated before and 6-12 months after implantation. The systolic dyssynchrony index (SDI) for all 16 LV segments was measured with both software packages and compared using Pearsons correlation and BlandAltman analysis  
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<br/><br/><label>Subjects--Index Terms: </label>Dyssynchrony  Software packages  Three-dimensional echocardiography