TY - BOOK AU - Mohamed Fathy Abdelzaher Aly AU - Hossam Ibraheem Kandil , AU - Khaled Aly Hassan Sorour , AU - Yasser Ahmed Abdelhady , TI - Use of real-time three dimensional echocardiography with semi-automatic endocardial contour detection for prediction of response to cardiac resynchronization therapy in patients with heart failure / PY - 2014/// CY - Cairo : PB - Mohamed Fathy Abdelzaher Aly , KW - Dyssynchrony KW - Software packages KW - Three-dimensional echocardiography N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology; Issued also as CD N2 - Background: Cardiac resynchronization therapy (CRT) is an established therapy in heart failure. However, one third of patients are non-responders, accordingly, proper selection of CRT eligible patients are essential. Aims: 1) To test their ability to predict response to CRT in patients with ischemic and non-ischemic cardiomyopathy. 2) To compare TomTec and QLAB software packages for the three-dimensional echocardiographic (3DE) assessment of left ventricular (LV) dyssynchrony. Methods and results: A total of 140 heart failure patients with the LVEF {u2264}35% and 60 healthy volunteers underwent 3DE. A subgroup of 60 patients underwent CRT and were evaluated before and 6-12 months after implantation. The systolic dyssynchrony index (SDI) for all 16 LV segments was measured with both software packages and compared using Pearson{u2019}s correlation and Bland{u2013}Altman analysis ER -