Amr Hussein Sayed

The use of two modern hydroxyethyl starch solutions in major urological procedures : Effect on acid-base status and renal functions / إستخدام نوعين من محلول هيدروكسي ايثيل النشا الحديث في عمليات المسالك البوليه الكبرى التأثير على التوازن الحمضي القلوي ووظائف الكلى Amr Hussein Sayed ; Supervised Ahmed Helmy Abdalsalam , Ahmed Mohamed Mukhtar , Nazmy Edward Seif - Cairo : Amr Hussein Sayed , 2014 - 91 P. : ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia

This study showed that both balanced 6% HES 130/0.4 (Tetraspan) and saline-based 6% HES 130/0.4 were equally effective for hemodynamic stabilization of patients undergoing major urologic procedures without any significant impact on acid base or renal functions. In the context of safety concerns that has been raised recently regarding the use of HES in critically ill patients, it is time to reevaluate the safety of using HES intraoperatively and whether we still need to continue using these solutions or not.the third generation of tetrastarches shows a signicantly improved safety prole without any loss of volume effect compared to rst- and second- generation HES preparations



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