Hend Mohammed Elsayed Sabry Abushady

Association of single nucleotide polymorphism in IL-12A and IL-12B with bronchial asthma in Egyptian children / العلاقه بين التغييرات الجينيه في الانترلوكين١٢(أ و ب) والربوالشعبى لدى الأطفال المصريين Hend Mohammed Elsayed Sabry Abushady ; Supervised Mona Mostafa Elfalaky , Nehal Mohammed Elrifai , Nadia Ibrahem Sewelem - Cairo : Hend Mohammed Elsayed Sabry Abushady , 2014 - 200 P. ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Asthma is a complex disease that is characterized by airway inflammation and bronchial hyperresponsiveness and results from an interaction of inherited and environmental factors. Large - scale genome screens have identified several chromosomes linked to the diagnosis of asthma. The IL12 gene is a potential candidate for asthma because of its role in regulating TH1 / TH2 response and it is also important in cell - mediated immunity



Bronchial asthma IL12 Single nucleotide polymorphism