Hossam Eldin Shaaban

Metformin as An ADD on therapy in the treatment of hepatitis C virus Egyptian patients / استخدام عقار الميتفورمين كعلاج إضافي لمرضى الالتهاب الكبدي الفيروسي سي المصريين Hossam Eldin Shaaban ; Supervised Taher Elzanaty , Ayman Foda , Sameh Seif Eldin - Cairo : Hossam Eldin Shaaban , 2013 - 98 P. : facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

HCV is a major health problem in Egypt. Combined therapy with pegylated interferon and ribavirin is the only evidence based treatment to HCV genotype 4. Insulin resistance is linked to non response to combined therapy. The study was carried out to study the effect of adding metfurmin to the combined therapy in patients with insulin resistance. Statistical studies were carried out on two groups. One group took triple therapy with pegylated interferon, ribavirin, and metfurmin. The second group took combined therapy. Statistical analysis revealed no significant dffirence between the two groups at week 72 (SVR)



HCV insulin resistance Interferon