Mohamed Badie Taher Kattaria <br/><br/>
Micronucleus assay as biomarker for chromosome malsegregation in young mothers with down syndrome children /  
 فحص النوييات فى الأمهات الشابات للأطفال المصابين بمتلازمة داون كدلاله بيولوجية لعيوب فصل الكروموسومات 
Mohamed Badie Taher Kattaria ; Supervised Sawsan Abdelhady Hassan , Hanan Hosny Afifi , Eman Abdelghany Abdelghany 
 - Cairo :   Mohamed Badie Taher Kattaria ,   2014 
 - 120 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics 
<br/><br/> We observed an increased frequency of binucleated micronucleated lymphocytes in mothers who had a down syndrome (DS) child before 30 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from malsegregation chromosome 21. The present study included 62 Egyptian young mothers (age < 30 y) ,free from any chronic disease, not taking any regular drugs, there were divided  into 2 groups: Group 1;  22 mothers of classic down syndrome children and Group 2; 40 healthy Egyptian matched females as control group 
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<br/><br/><label>Subjects--Index Terms: </label>Chromosome Down syndrome Micronucleus