TY  - BOOK
AU  - Aya Zeiada Mohamed
AU  - Dalia Ahmed Khairy , 
AU  - Heba Hany Abu Hussein , 
AU  - Rania Ahmed Zayed , 
TI  - A comparative randomized study of safety and efficacy of once versus twice daily dose of amikacin in treatment of neonatal sepsis / 
PY  - 2014///
CY  - Cairo : 
PB  - Aya Zeiada Mohamed , 
KW  - Amikacin
KW  - Aminoglycosides
KW  - Neonatal sepsis
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Neonates frequently receive amikacin as empiric therapy for severe infections caused by suspected Gram - negative bacteria. Optimum dosing of amikacin is required because of the inter - individual variability in the pharmacokinetics in the neonatal population. This study was conducted to compare the efficacy and safety (nephrotoxicity) of once daily versus twice daily dosing of amikacin in suspected or proven sepsis in neonates in relation to the pharmacokinetics of the drug as well as amikacin pharmacokinetic parameters determination under these two dosing schedules in the septic neonates of the Egyptian population
UR  - http://172.23.153.220/th.pdf
ER  -