TY - BOOK AU - Marwa Salah Elsayed Shabana AU - Azza Ahmed Aboulenein , AU - Hanan Elsayed Ali Darweesh , AU - Samia Mohamad Hassan Fadda , TI - Evaluation of the classical complement pathway in activation of rheumatoid arthritis / PY - 2014/// CY - Cairo : PB - Marwa Salah Elsayed Shabana , KW - Classical complement pathway KW - Disease activity parameters KW - Rheumatoid arthritis N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation; Issued also as CD N2 - Complement activation has been implicated in the pathogenesis of RA. C1q {u2013} C4 complexes are a specific parameter of classical pathway activation. We aimed to investigate plasma levels of complement parameter; C1q and activated C4 in rheumatoid arthritis, and also to assess their association with disease activity. 50 RA patients classified into inactive RA group whose DAS 28 < 2.6 (n = 23 / 50) and active group had DAS 28 {u2265} 2.6 (n = 27 / 50) and control group (n = 20). RA patients were submitted to full history taking, full clinical examination, routine laboratory investigations, assessment of disease activity. CIq antibodies and C4d antibodies were measured using enzyme - linked Immunosorbent assay (ELISA) technique UR - http://172.23.153.220/th.pdf ER -