Asmaa Salem Shanab <br/><br/>
Immunohistochemical expression of claudin 1 in oral squamous cell carcinoma /  
 دراسة مناعية نسجية كيميائية للكشف عن كلودين ١ فى سرطان الخلايا الحرشفية فى الفم 
Asmaa Salem Shanab ; Supervised Mohsen Kazem Abdellatif , Dina Soliman Khater  
 - Cairo :   Asmaa Salem Shanab ,   2013 
 - 87 P. :   photographs ;   30cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology 
<br/><br/> Tight  junctions (TJs) are the most apical intercellular junctions, play major play major roles in controlling apical / basolateral polarity and acting as paracellular barriers. Furthermore, they are also known to participate in the control of fproliferation and differentiation. It is now well - established that dys - regulation o these functions contributes to initiation and progression of cancer. It has become clear that the claudins, members of a large family of 27 closely related transmembrane proteins, play a crucial role in formation, integrity and function of TJs. Some authors investigated the expression of claudin - 1 (Cldn - 1) in different human cancers 
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<br/><br/><label>Subjects--Index Terms: </label>Claudin - 1 Immunohistochemistry and Oral squamous cell carcinoma Tight junctions