TY - BOOK AU - Asmaa Salem Shanab AU - Dina Soliman Khater , AU - Mohsen Kazem Abdellatif , TI - Immunohistochemical expression of claudin 1 in oral squamous cell carcinoma / PY - 2013/// CY - Cairo : PB - Asmaa Salem Shanab , KW - Claudin - 1 KW - Immunohistochemistry and Oral squamous cell carcinoma KW - Tight junctions N1 - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology; Issued also as CD N2 - Tight junctions (TJs) are the most apical intercellular junctions, play major play major roles in controlling apical / basolateral polarity and acting as paracellular barriers. Furthermore, they are also known to participate in the control of fproliferation and differentiation. It is now well - established that dys - regulation o these functions contributes to initiation and progression of cancer. It has become clear that the claudins, members of a large family of 27 closely related transmembrane proteins, play a crucial role in formation, integrity and function of TJs. Some authors investigated the expression of claudin - 1 (Cldn - 1) in different human cancers UR - http://172.23.153.220/th.pdf ER -