Mary Yosry Aziz Faragallah <br/><br/>
Formulation and evaluation of controlled release parenteral in situ forming drug delivery system /  
 صاغة و تقم أنظمة توصل منضبطة الانطلاق متكونة فى الموضع عن طرق الحقن 
Mary Yosry Aziz Faragallah ; Supervised Soad A. Yehia , Sally A. Abdelhalim 
 - Cairo :   Mary Yosry Aziz Faragallah ,   2014 
 - 175 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics 
<br/><br/> The aim of this thesis is to formulate controlled release in situ forming implants (ISI) and in situ forming microparticles (ISM) containing lornoxicam for management of postoperative and arthritic pain in order to decrease dosing frequency and increase patient compliance.  Polymeric in situ implant solutions were prepared using different concentrations of Poly - DL - lactide (PDL) or DL - lactide/glycolide copolymer (PDLG) solutions with different inherent viscosities in N methyl pyrrolidone (NMP) using 2² X 4 factorial experimental design, where sixteen formulae were prepared. Non polymeric in situ implant solutions prepared using different concentrations of lipids like cetyl alcohol and stearyl alcohol and also sucrose acetate isobutyrate (SAIB) using 3² factorial experimental design, resulting in nine formulae 
<br/><br/>
<br/><br/><label>Subjects--Index Terms: </label>In situ forming implant in situ forming microparticles Lornoxicam