TY  - BOOK
AU  - Asmaa Mohamed Abougabal 
AU  - Amal Hassan Abdelrahman  , 
AU  - Amina Kamel Amin , 
TI  - Immunohistochemical expression of vascular cell adhesion molecule-1 in salivary gland tumors / 
PY  - 2013///
CY  - Cairo : 
PB  - Asmaa Mohamed Abougabal , 
KW  - Claudin 1
KW  - Immunohistochemistry and oral squamous
KW  - Tight junctions
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology; Issued also as CD
N2  - Background: In recent years, the involvement of adhesion molecules in tumor development and formation of metastatic foci has become an object of research. Scientists have been trying to determine the significance of their expression in early diagnosis, in the assessment of cancer stage and metastatic development. Their role in local tumor growth, in the formation of distant metastases and involvement in angiogenesis has been investigated. The study was conducted to investigate salivary gland tumors for the following: Immunohistochemical expression of VCAM-1 and the relationship between VCAM-1 as regard tumor malignancy grade, tumor angiogenesis and MVD. Materials and methods: Fourty eight paraffin blocks of salivary gland neoplasms (13 benign and 35 malignant), in addition to five specimens of normal minor salivary glands that served as a control, were immunohistochemically stained with VCAM-1 antibody. ANOVA and Tukey's tests were used for the statistical analysis, to compare between the control and the different types of benign and malignant salivary gland neoplasms. Results:VCAM-1 immunoreactivity has been detected in normal and   tumor tissues. The reaction was observed in tumor  cells as well as intratumoral and peritumoral  ECs, especially in vessel abundant regions
UR  - http://172.23.153.220/th.pdf
ER  -