TY - BOOK AU - Mohamed Wagih Mahmoud AU - Ahmed Mohamed Mukhtar , AU - Aiman Adel Dessouki , AU - Maged Salah Abdullah , TI - Acute permissive hypercapnia during one lung ventilation : : Impact on right ventricular function during lung resection / PY - 2014/// CY - Cairo : PB - Mohamed Wagih Mahmoud , KW - One lung ventilation KW - Permissive hypercapnia KW - Right ventricle N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia; Issued also as CD N2 - In a quasi - experimental design study, the haemodynamic and gas exchange effects of acute permissive hypercapnia and its effect on right ventricle during one - lung ventilation in thoracotomy patients were investigated. The effects of normocapnic and hypercapnic one - lung ventilation in 15 patients undergoing pulmonary resection were compared. Hypercapnia was induced by decreasing tidal volume until PaCO2 increased to 60 - 70 mm Hg. Cardiac index (from 2.93 ± 0.44 to 3.37 ± 0.54 l min - 1 m - 2, P value < 0.001), tricuspid annular plane systolic excursion (2.16 ± 0.15 to 2.4 ± 0.17 cm, P value <0.001) and right ventricular myocardial performance index (0.319±0.01 to 0.33 ± 0.0, P value < 0.001) increased with hypercapnia. Systemic and pulmonary oxygenation improved UR - http://172.23.153.220/th.pdf ER -