Hisham Adel Abdelfatah Moustafa <br/><br/>
Proton MR spectroscopy of the breast using the total choline peak Integral as A marker of malignancy and its histological grading /  
 بروتون التحليل الطيفى بالرنين المغناطيسى للثدى باستخدام إجمالى الذروة الكولين كعلامة من الخباثة و الدرجات النسيجية 
Hisham Adel Abdelfatah Moustafa ; Supervised Naglaa Mohamed Abdelrazek , Hossam Eldin Hussien , Omar Sherif Omar 
 - Cairo :   Hisham Adel Abdelfatah Moustafa ,   2014 
 - 110 Leaves :   facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis 
<br/><br/> MR spectroscopy of the breast is a recently described noninvasive method that has shown promising results in differentiating benign from malignant lesions. High levels of composite choline are likely to be found in malignant lesions. Low choline levels expected in benign lesions and normal breast tissues in our study we aim to correlate the total choline peak in MR Spectroscopy with histo -pathological grading of breast carcinoma. Proton MRS has been shown to characterize breast tissues because of the ability to detect the resonances arising from the tri-methylammonium head groups of the total pool of water-soluble choline-containing metabolites. choline containing metabolites at t 3.2 pp 
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<br/><br/><label>Subjects--Index Terms: </label>Breast tumors MR imaging MR spectroscopy