TY - BOOK AU - Heba Elsayed Ahmed Teba AU - Aliaa Mohamed Kamal , AU - Mohammed Abdalrahman Shaaban , AU - Nadia Ahmed Abdo , TI - Application of diazo coupling reactions in synthesis of new heterocyclic compounds of pharmaceutical interest / PY - 2014/// CY - Cairo : PB - Heba Elsayed Ahmed Teba , KW - Diazocoupling KW - Heterocyclic compounds KW - N- containing compounds N1 - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry; Issued also as CD N2 - This thesis comprises five parts, the first part is an introduction about diazocoupling reactions and synthesis of benzimidazoles. The second part clarifies the rationale for the synthesis of the targeted compounds. The third part deals with the theoretical diazocoupling of the experimental work in preparation of compounds {u2160} - XX{u2160}. The structures were supported by elemental analysis, {u2160}R, ¹H NMR, ¹³C NMR mass spectral data and TLC monitoring. In the fifth part, biological activity was evaluated in - vitro growth of three human tumor cell lines, MCF -7) (NC{u2160} - H460), and (SF - 268) and compared with doxorubicin ER -