Phenotypic and molecular characterization of multidrug - resistant acinetobacter baumannii isolated from hospitalized patients /
التوصيف الظاهرى و الوراثى لبكتريا الأسينتوباكتر المتعددة المقاومة و المسببة للعدوى بين المرضى بالمستشفيات
Mahmoud Abdelati Fouad Khalil ; Supervised Abdelgawad M. Hashem , Wael Mostafa Tawakkol , Ahmed Sherif Mohamed Hussein Attia
- Cairo : Mahmoud Abdelati Fouad Khalil , 2014
- 137 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
During the last decades, Acinetobacter baumannii become a global problem that threatens many health care settings. A. bammunnii is characterized by its extraordinary ability to persist in the environment. Moreover, it has a magnificence ability to acquire and express multiple resistance mechanisms against major antibiotic classes. There is no unique bacterial metabolic test that can differentiate it from other non - lactose fermenter gram negative bacteria; furthermore, the pathogenicity of Acinetobacter species is not the same. A. baumannii species are the most frequently involved in severe infections. The present study aimed to characterize the prevalence of MDR - A. bammunnii in Egyptian hospital; Identify their antimicrobial susceptibility level; phenotypic characterization of resistance mechanisms; molecular identification of class D and metallo - Ý - lactamase; molecular typing of IMRAB and apply nano - gold assay using unmodified AuNPs for rapid detection of A. baummnnii
Acinetobacter baumannii Gold nanoparticles Imipenem resistant A. baumannii