TY - BOOK AU - Samah Shaaban Zaki AU - Mahasen Mabrouk , AU - Mohammad Elbeshlawy , AU - Wafaa Ahmed Alakel , TI - Clinical biochemical and histological profile of chronic hepatitis C patients with normal serum aminotransferases / PY - 2014/// CY - Cairo : PB - Samah Shaaban Zaki , KW - ALT KW - AST KW - Chronic HCV N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine; Issued also as CD N2 - Hepatitis C virus (HCV) is a major public health problem and is considered the most common etiology of chronic liver disease in Egypt. Chronic hepatitis C virus (HCV) patients with persistently normal transaminases represent a subgroup of patients with mild, slowly progressive disease, natural history, and optimal management of these patients needs to be investigated in Egypt. To assess the severity of hepatic fibrosis and response to therapy in a cohort of Egyptian HCV patients with normal transaminases. Retrospective demographics, laboratory, histological features and treatment outcome of patients included in the national program for the control of viral hepatitis in Egypt since 2008 - 2012 were collected. Combined pegylated IFN / ribavirin therapy was given for patients with fibrosis stage {u2265} F1 and elevated transaminases while those with normal transaminase; therapy was initiated only in patients with fibrosis stage {u2265} F2 ER -