TY  - BOOK
AU  - Shrouk Moataz Sayed Abdallah
AU  - Aisha Mahmoud Elmarsafy , 
AU  - Ilham Youssry Ibrahim , 
AU  - Nermeen Mouftah Galal , 
TI  - Detection of complications following intravenous immunoglobulin infusion in children / 
PY  - 2013///
CY  - Cairo : 
PB  - Shrouk Moataz Sayed Abdallah , 
KW  - Children
KW  - Compications  inhravs immunoglobulin
KW  - Intravenous immunoglobulin infusion
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Background: Intravenous immunoglobulins (IVIGs) are scarce biological products used in a broad variety of disorders. Tolerance to infusions is usually good but adverse events, including some serious ones, have been reported. Aim of the work: The study aimed for detection of adverse events that occur during and following intravenous immunoglobulin (IVIG) infusion; in relation to preparation, dosing regimen, duration and infusion hours, with identification of patients at risk of developing these adverse events. Patients and methods: To detect the complications of IVIG infusions, an observational study was implemented on a cohort of 55 patients (birth to18 years) who received 62 infusion sessions for different disease conditions over a period of 6 months, 2013. Clinical evaluation and laboratory assessment were done with follow up 7-10 days afterwards.      Results: Adverse events occurred following 37.1% of IVIG infusions ranging from common mild rate related reactions such as skin rash, fever and chills to more severe anaphylactoid ones as serum sickness (3.2%) and rare ones such as significant anemia (22.6%) and acute renal failure (3.2%). Infusion rate and the presence of risk factors are strong predicting variable for numerous reactions
ER  -