TY  - BOOK
AU  - Ahmed Mohamed Eldeeb
AU  - Gamal Eldin Esmat , 
AU  - Mohamed Ali Saber , 
AU  - Wahid Halim Doss , 
TI  - Single nucleotide polymorphism (SNP) rs8099917 as a predictive factor of virological response to pegylated interferon plus ribavirin in treatment of chronic hepatitis C virus patients / 
PY  - 2014///
CY  - Cairo : 
PB  - Ahmed Mohamed Eldeeb , 
KW  - HCV
KW  - Interleukin 28b SNP rs8099917
KW  - Pegylated interferon
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine; Issued also as CD
N2  - Introduction: For  SNP rs8099917, the favorable T allele is associated with a higher SVR after PEG - IFN alpha/RBV therapy while the G allele is a risk factor for non - response. Aim of work: Is to assess the value of (SNP) rs8099917 as a predictor of SVR. Methods: This study is a retrospective controlled study and was performed on a total number of 240 patients who were treated by PEG - IFN alpha/RBV for 48 weeks and (SNP) rs8099917 was done for the all patients. Results: TT genotype was more prevalent in SVR group than TG and GG genotypes. Conclusion: Determination of (SNP) rs8099917 before starting antiviral therapy may thus serve as a good response predictor
UR  - http://172.23.153.220/th.pdf
ER  -