Tamer Ali Adel Khlosy <br/><br/>
Synthesis and evaluation of biological activity of some new polynuclear heterocyclic compounds containig nitrogen /  
 تحضر و تقم النشاط البولوجى لبعض المركبات متعددة الحلقات غر المتجانسة والتى تحتوى على نتروجن 
Tamer Ali Adel Khlosy ; Supervised Hussein F. Zohdi , Nora M. Rateb 
 - Cairo :   Tamer Ali Adel Khlosy ,   2014 
 - 172 Leaves :   charts ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry 
<br/><br/> This work has been carried out to investigate chemical reactivity and synthetic potentiality of 3-cyano-2- pyridinethione via its reaction with various reagents such as halogen containing compounds to afforded Thieno [2,3-b] pyridine derivatives. 2- Hydrazinylpyridine-3-carbonitrile and 3- aminopyrazolopyridine through the reaction of 3-cyano-2- pyridinethione derivatives with hydrazine hydrate . Structures of the newly synthesized compounds were elucidated by using elemental analyses and spectroscopic techniques such as IR , Mass spectrometry , and 1 H NMR . Structures of some of the newly synthesized compounds were confirmed via alternative synthesis . Antimicrobial activity of some of the final products were examined  
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<br/><br/><label>Subjects--Index Terms: </label>3-cyano-2- pyridinethione derivatives  New polynuclear heterocyclic compounds Synthesis