Ingy Gamal Eldin Elshenawy  Mohamed <br/><br/>
Autologous bone marrow-derived stem cell transplantation in patients with chronic liver diseases /  
 تأثير زراعة الخلايا الجذعية الذاتية على مرضى أمراض الكبد المزمنة 
Ingy Gamal Eldin Elshenawy Mohamed ; Supervised Nouman Mohammed Hassaan Elgarem , Mona Ahmed Amin Soliman , Hala Gabr Metwalli 
 - Cairo :   Ingy Gamal Eldin Elshenawy  Mohamed ,   2014 
 - 159 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine  
<br/><br/> Liver transplantation is the only current therapeutic modality for liver failure, but due to the shortage of organ donors, it is available to only a small proportion of patients. Adult stem cell therapy could solve the problem of degenerative disorders, including liver disease, in which organ transplantation is inappropriate or there is a shortage of organ donors.  This study aimed at evaluating the effect of autologous transplantation of BM-derived mononuclear cells subjected to ex vivo hepatocyte differentiation and BM-derived undifferentiated mesenchymal stem cells  in cirrhotic patients, and at assessing the safety and efficacy of transplantation of these cells via direct intrasplenic injection 
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<br/><br/><label>Subjects--Index Terms: </label>Chronic liver diseases  Liver diseases Stem cell transplantation