TY - BOOK AU - Ingy Gamal Eldin Elshenawy Mohamed AU - Hala Gabr Metwalli , AU - Mona Ahmed Amin Soliman , AU - Nouman Mohammed Hassaan Elgarem , TI - Autologous bone marrow-derived stem cell transplantation in patients with chronic liver diseases / PY - 2014/// CY - Cairo : PB - Ingy Gamal Eldin Elshenawy Mohamed , KW - Chronic liver diseases KW - Liver diseases KW - Stem cell transplantation N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine; Issued also as CD N2 - Liver transplantation is the only current therapeutic modality for liver failure, but due to the shortage of organ donors, it is available to only a small proportion of patients. Adult stem cell therapy could solve the problem of degenerative disorders, including liver disease, in which organ transplantation is inappropriate or there is a shortage of organ donors. This study aimed at evaluating the effect of autologous transplantation of BM-derived mononuclear cells subjected to ex vivo hepatocyte differentiation and BM-derived undifferentiated mesenchymal stem cells in cirrhotic patients, and at assessing the safety and efficacy of transplantation of these cells via direct intrasplenic injection UR - http://172.23.153.220/th.pdf ER -