TY - BOOK AU - Shymaa Elsayed Ayoub AU - Maisa Said Elrazki , AU - Olfat Gamil Shaker , AU - Yassser Hussein Nassar , TI - Influence of vitamin D receptor gene polymorphisms on treatment of chronic HCV patients with interferon / PY - 2014/// CY - Cairo : PB - Shymaa Elsayed Ayoub , KW - Hepatitis C KW - Polymorphism KW - Vitamin D N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry; Issued also as CD N2 - Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. Our aim is to detect the Influence of Vitamin D receptor gene polymorphisms (BsmI) and (Fok1) and Vit. D level in the blood of chronic liver disease patients under treatment with interferon. Blood samples were taken from 103 patients who are suffering from chronic hepatitis C disease. They were divided into Respoders (n = 63)and Non- Responders (n = 40)according to their initial response to treatment with normalization of aminotransferases (ALT and AST) levels and clearance of the virus denoted by negative HCV - RNA by PCR after 6 months of receiving treatment UR - http://172.23.153.220/th.pdf ER -