Essam Ali Mohamed Ali

Vitamin D serum level and CYP27B1-1260 promoter polymorphism in chronic hepatitis C patients treated with interferon / فى مرضى الالتهاب الكبدى الوبائى سى المعالجين بالانترفيرون CYP27B1-1260 مستوى فيتامين د فى مصل الدم و التعدد الجينى للنقطة Essam Ali Mohamed Ali ; Supervised Olfat Gamil Shaker , Samar Ali Marzouk , Gamal Essmat - Cairo : Essam Ali Mohamed Ali , 2014 - 87 P. ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry

Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus infection varies between individuals. We aimed to determine the incidence of vitamin D deficiency in patients with chronic hepatitis C. In addition, we evaluated associations of vitamin D (Vit D) serum levels as well as polymorphism within gene encoding 1Ü- hydroxylase with the virologic response of interferon - Alfa based treatment in patients chronically infected with HCV in Egypt. Blood samples were taken from 103 patients who are suffering from chronic hepatitis C disease and prepared for interferon treatment. Also 30 blood samples from controls were taken



Hepatitis C Polymorphism Vitamin D