TY - BOOK AU - Essam Ali Mohamed Ali AU - Gamal Essmat , AU - Olfat Gamil Shaker , AU - Samar Ali Marzouk , TI - Vitamin D serum level and CYP27B1-1260 promoter polymorphism in chronic hepatitis C patients treated with interferon / PY - 2014/// CY - Cairo : PB - Essam Ali Mohamed Ali , KW - Hepatitis C KW - Polymorphism KW - Vitamin D N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry; Issued also as CD N2 - Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus infection varies between individuals. We aimed to determine the incidence of vitamin D deficiency in patients with chronic hepatitis C. In addition, we evaluated associations of vitamin D (Vit D) serum levels as well as polymorphism within gene encoding 1Ü- hydroxylase with the virologic response of interferon - Alfa based treatment in patients chronically infected with HCV in Egypt. Blood samples were taken from 103 patients who are suffering from chronic hepatitis C disease and prepared for interferon treatment. Also 30 blood samples from controls were taken UR - http://172.23.153.220/th.pdf ER -