The association between serum adhesion molecules and outcome in acute spontaneous intracerebral hemorrhage /
العلاقة بين الجزيئات اللاصقة بالدم ومصير النزيف التلقائى بالمخ
Hisham Mohamed Soliman Omara ; Supervised Ahmed Hussein Alsherif , Amal Fouad Rizk , Ashraf Hussein Abdalmohsen
- Cairo : Hisham Mohamed Soliman Omara , 2014
- 176 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine
Background: Serum concentrations of adhesion molecules may be connected to the pathogenesis of secondary brain injury after spontaneous intracerebral hemorrhage (ICH). This study posits the hypothesis that levels of adhesion molecules substantially increase after ICH and are decreased thereafter, and that they can predict treatment outcomes. Methods: Our study was conducted as a prospective study on 25 patients with acute spontaneous ICH presenting to ER of EL Sahel teaching hospital over a period of 19 months (May 2012 to November 2013) confirmed by patient history and brain CT scan, who were investigated with serial serum levels of adhesion molecules (sICAM) during their hospital stay compared to levels in control group. The studied population was divided into two groups; group 1(25 patients) with acute ICH and group 2(25) young volunteers. The case group was divided as regards the outcome into two subgroups; bad outcome and good outcome by using the modified Rankin Disability Scale (mMRS)