TY  - BOOK
AU  - Basma Serag Eldin Alsayed Habib
AU  - Afaf Hussein Elmasry , 
AU  - Kamelia Mahmoud Amin , 
TI  - Synthesis and biological evaluation of some novel phthalimide derivatives incorporated into other heterocycles as anticancer and antimicrobial agents / 
PY  - 2014///
CY  - Cairo : 
PB  - Basma Serag Eldin Alsayed Habib , 
KW  - Phthalimides
KW  - Ring closure reactions
KW  - Thiazoles and other heterocycles
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry; Issued also as CD
N2  - The phthalimide moiety has been utilized extensively in medicinal chemistry and is considered to be a privileged structure that shows various pharmacological activities including anti inflammatory, hypoglycemic, hypolipidemic, anticonvulsant, anxiolytic, antiviral, antitumor and antimicrobial activity. Therefore, we are considered with the synthesis of novel series of substituted (4- substituted phenylamino) methyl phthalimides with the objective of discovering novel antitumor antimicrobial agents. Moreover docking of the some biologically tested compounds into the active site of GyrB enzyme was performed to correlate the docking results with the biological results
UR  - http://172.23.153.220/th.pdf
ER  -