TY  - BOOK
AU  - Zainab Zakaria Ali Zenhom
AU  - Mahmoud Ahmed Amer , 
AU  - Sayed Fekry Abdelwahab , 
TI  - Evaluation of cell responses against hepatitis C virus antigens among Egyptian healthcare workers at high risk of infection / 
PY  - 2014///
CY  - Cairo : 
PB  - Zainab Zakaria Ali Zenhom , 
KW  - Cell mediated immunity
KW  - HCV
KW  - Healthcare workers
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology; Issued also as CD
N2  - Hepatitis C Virus (HCV) specific cell-mediated immunity (CMI) has been reported among exposed individuals without viremia or seroconversion. Limited data are available regarding CMI among at - risk, seronegative, aviremic Egyptian healthcare workers (HCW), where HCV genotype 4 predominates. We investigated CMI responses among HCW at the National liver institute, where over 85% of the patients are HCV - infected. We quantified HCV - specific CMI in 52 seronegative aviremic Egyptian HCW using an interferon gamma (IFN - Þ) enzyme-linked immunospot (ELISpot) assay in response to 7 HCV genotype 4a overlapping 15mer peptide pools covering most of the viral genome. We also characterized the phenotype of the responding T cells to the HCV peptide pools by flow cytometry
UR  - http://172.23.153.220/th.pdf
ER  -