TY - BOOK AU - Mohammed Mustafa Mohammed AU - Dawlat Belal , AU - Khalid Kaffas , AU - Manal Eldeeb , TI - Relationship between matrix metalloproteinase 10 (MMP-10) and atherosclerosis in patients with chronic kidney disease / PY - 2014/// CY - Cairo : PB - Mohammed Mustafa Mohammed , KW - Atherosclerosis KW - MMP 10 KW - Renal failure N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine; Issued also as CD N2 - Cardiovascular diseases (CVD) are the leading cause of death in patients with chronic kidney disease (CKD). As matrix metalloproteinases have a major role in atherosclerosis, we investigated the relationship between MMP 10 and severity of atherosclerosis in patients with chronic kidney disease. This was evaluated in a cross sectional, observational study of 30 patients with different stages of kidney disease, 30 patients on dialysis and 20 controls. The severity of atherosclerosis was estimated with carotid intima media thickness (CIMT) by carotid ultrasound. Serum levels of the matrix metalloproteinase 10 (MMP 10) was measured by ELISA and were significantly increased in patients with kidney disease compared with the healthy controls, and higher in patients on dialysis than in earlier stages of CKD UR - http://172.23.153.220/th.pdf ER -