Baroreflex integrity : A comparative study between propofol, sevoflurane and propofol with sevoflurane anesthesiab /
سلامة منعكس المستقبل الضغطى : دراسة مقارنة بين التخدير باستخدام البروبوفول: السيفوفلوران أو البروبوفول مع السيفوفلوران
Mona Hamed Elsherbiny ; Supervised Tarek Mahmoud Fahmy Abdelbarr , Jehan Helmy Ibrahim , Ahmed Abdalla Mohamed
- Cairo : Mona Hamed Ahmed Elsherbiny , 2014
- 123 Leaves : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia
The baroreceptor reflex is the main mechanism for short - term regulation of blood pressure and a major determinant of the blood pressure responses associated with various behaviors. Baroreflex sensitivity (BRS) is the amount of change in beat - to - beat interval (RR) against a 1mm Hg systolic blood pressure deviation. BRS is traditionally measured by bolus injection of vasoactive drugs such as phenylephrine which causes increase in systolic blood pressure (SBP) or Na nitroprusside (NTP) which causes decrease in systolic blood pressure. This comparative study included 60 patients who were scheduled for laparoscopic gynecological surgery. Patients were divided into three groups (Propofol - group) , (Sevo - group) and (combined propofol and Sevo group) with 20 patient in each group. Pressor and depressor tests were done pre,intra and postoperative with recording systolic blood pressure and R - R interval as well as the diastolic overshoot in the awake atate,under anesthesia and postoperatively