Thyroid hormones abnormalities in patients with liver cirrhosis and their relation to disease severity /
اضطراب وظائف الغدة الدرقية فى مرضى التليف الكبدى و علاقتها بتدهور حاله الكبد
Abeer Awad Abdelhady ; Supervised Mona Radwan , Ula Mabid Aljarhi , Mona Mohsen Abdelsalam
- Cairo : Abeer Awad Abdelhady , 2014
- 129 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
The most common thyroid hormone profile in patients with cirrhosis is a low total and free T3 and an elevated rT3, similar to NTIS (nonthyroidal illness syndrome) pattern. Also, the association between thyroid diseases and hepatocellular carcinoma (HCC) has not been well established. The aim of this work was to study the thyroid hormone status in patients with liver cirrhosis. Also, to correlate thyroid functions with hepatic status in compensated and decompensated cirrhosis, and to study the effect of thyroid dysfunction in development and prognosis of HCC. The study included 58 patients. Clinical assessment, liver function tests and abdominal ultrasound ± CT abdomen were done. 39 patients had decompensated liver cirrhosis, 11 patients had compensated liver cirrhosis and 8 patients had HCC. The study included 12 healthy controls. TSH, FT4 and FT3 were done to all subjects