In vivo comparison of bio - gen and nano bone in surgically induced defects in rabbit tibia : Histological, morphometric and radiographic studies /
مقارنة داخل الحيوان بين البايو- جين و عظم النانو فى العيوب المسببه جراحيا فى ساق الأرنب : دراسات نسيجيه: مورفومتريه و تصوير شعاعى
Israa Ahmed Gamal Eldin Radwan ; Supervised Nahed Sedky korany , Heba Mohamed Hakam
- Cairo : Israa Ahmed Gamal Eldin Radwan , 2014
- 134 Leaves : photographs ; 30cm
Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Biology
The aim of the present research was to compare the osteoconductivity of both bio - gen and nano bone after implantation in experimental osseous defects in rabbit tibia. Thirty adult male New zealand white rabbits were used in the study. Two holes, 1 cm apart, were created in each tibia reaching the bone marrow. The lower hole of the right tibia was packed with bio - gen material, while the upper hole was left empty to serve as control. In the left tibia nano bone was packed in the lower hole while the upper hole was left empty to serve as control. Histological analysis revealed a more accelerated pattern of bone healing in the graft augmented bone defects as compared to the control defects. Furthermore, the Nano - bone augmented defect showed a more advanced pattern of bone healing than the bio - gen augmented bone defects histomorphometric analysis showed the highest bone area percentage in the nano bone defect, followed by the bio - gen defect and the control defect. Furthermore, the highest bone mineral density was recorded in the nano bone defect followed by the Bio-gen and the control defects