Asmaa Ahmed AbdElAal <br/><br/>
Gata 1 and gata 2 gene expression in myelodysplastic syndromes MDS /  
 التعبير الجينى لجاتا 1 و جاتا 2 فى حالات متلازمة سوء النمو النخاعى 
Asmaa Ahmed AbdElAal ; Supervised Laila Abd El rahman Hegazi , Mervat Mohamed Wageh Mattar , Saher Kamal_Eldin Hussein 
 - Cairo :   Asmaa Ahmed AbdElAal ,   2006 
 - 119p :   ill ;   25cm 
<br/><br/>Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology 
<br/><br/> GATA - 1 and GATA - 2 are 2 transcription factors playing important role in gene regulation during development and differentiation of haematopoietic cellsWhile GATA - 2 is essentially involved in the regulation of proliferation / self renewal of early haematopoietic cells , GATA - 1 is required for terminal differentiationSince inappropriate hematopoietic differentiation results in varying degree of myelodysplasia , which is the hallmark of MDS , GATA - 1 and GATA - 2 genes expression patterns were suspected to be associated with MDS 
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<br/><br/><label>Subjects--Index Terms: </label>GATA - 1 GATA - 2 Transcription factors