TY  - BOOK
AU  - Noha Mohamed Sayed Mohamed
AU  - Ahmed soltan Monem , 
AU  - Nihal Saad Elbialy , 
TI  - Enhancement of cancer therapy using multifunctional gold nanoparticles formulations / 
PY  - 2014///
CY  - Cairo : 
PB  - Noha Mohamed Sayed Mohamed , 
KW  - Cancer
KW  - Chemotherapy
KW  - Gold nanoparticles
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics; Issued also as CD
N2  - Current non-targeted chemotherapy and radiotherapy  protocols causes marked cytotoxicity to critical organs in human. This thesis advances two multifunctional near infra-red (NIR)  absorbing gold nanoparticles to target breast cancer cells in-vitro and  Ehrlich carcinoma in-vivo. The two developed formulations, gold  nanoshells with mesoporous silica core (PEG-DOX-MPS-GNSs) and  gold nanorods coated mesoporous silica (pGNRs@mSiO2-DOX), can  both convert near infrared light energy into heat causing thermal  damage to cancerous cells. Further, the incorporated mesoporous  silica exhibit high drug loading capacity that can specifically deliver  the anticancer drug doxorubicin into tumor site and release it in  response to the acidic tumor microenvironment
UR  - http://172.23.153.220/th.pdf
ER  -