TY - BOOK AU - Mohammed Mahmoud Fathy Ahmed AU - Nihal Elbialy , AU - Wafaa A. Khlial , TI - Enhancement of the therapeutic efficacy of anticancer drug using magnetic gold nanocarriers / PY - 2014/// CY - Cairo : PB - Mohammed Mahmoud Fathy Ahmed , KW - Doxorubicin KW - Magnetic targeted drug delivery (MTD KW - Nanoparticles N1 - Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics; Issued also as CD N2 - Treatment of approximately 50% of human cancers includes the use of chemotherapy. The major problem associated with chemotherapy is the inability to deliver pharmaceuticals to specific site of the body without inducing normal tissue toxicity. Consequently, the efficiency of chemotherapy could potentially be improved by the development of a targeted drug nanocarriers that would enhance the effective water solubility of hydrophobic anticancer drugs as well as the selective delivery of drugs to malignant tissues. Thereby increasing the curative effectiveness of the cancer treatment while sparing normal tissues from the side effects of the chemotherapeutic agent ER -