Mohamed Abdelmohsen Zaki Mostafa

MN1 and PTEN gene expression in acute myeloid leukemia / فى سرطان الدم النخاعى الحاد PTEN و MN1 التعبير الجينى لكل من Mohamed Abdelmohsen Zaki Mostafa ; Supervised Rania Ahmed Zayed , Maha Abdelhameed Eltaweel , Shahira Kamal Anis - Cairo : Mohamed Abdelmohsen Zaki Mostafa , 2014 - 134 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Background: AML is a heterogeneous disease in clinical character and molecular genetics, we can detect many kinds of abnormal expression of genes. Among them, meningioma 1 (MN1) high expression and phosphatase and tensin homolog (PTEN) low expression are thought to be correlative with incidence of leukemia. Aim of the study: The aim of this study is to determine the expression and prognostic impact of MN1 and PTEN mRNA in AML cells by Real time Reverse Transcription-PCR and to correlate the their expression with other clinical and laboratory prognostic factors



Acute myeloid leukemia MN1 PTEN