Estimation of interleukin-21 levels in gingival crevicular fluid of patients with chronic periodontitis before and after non-surgical periodontal treatment /
ت ا 21 ا اى اى ل السني لدي المصابين بالتهاب الانسجة الدعامة ما حول السنية المزمن قبل و بعد العلاج الغير جراحي للثة
Yasmine Kamal Ramadan ; Supervised Samar Elkholy , Noha Ghallab , Olfat Shaker
- Cairo : Yasmine Kamal Ramadan , 2014
- 110 Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology
Background: The purpose of present study was to evaluate IL-21 levels in the gingival crevicular fluid of patients with chronic periodontitis before and after non- surgical periodontal therapy in an attempt to assess its role as a diagnostic and prognostic biomarker of periodontal destruction. Subjects and methods: The present study was conducted on 25 individuals Ten of the individuals were healthy and representing the control group, group (A) and 15 were suffering from chronic periodontitis representing group (B). Gingival crevicular fluid samples were collected from both study groups to detect IL-21 levels. Regarding the assessment of IL-21, ELISA technique was used. Group (B) was subjected to scaling and root planing and then were recalled after 4 months from treatment to resample the gingival crevicular fluid and evaluate the changes in clinical parameters after the nonsurgical periodontal treatment. Then all the detected data was subjected to statistical analysis