TY  - BOOK
AU  - Hebatollah Khaled Mohamed Rizk
AU  - Naglaa Mohamed Elhosary , 
AU  - Safa Fathy Abdelghani , 
TI  - Immunohistochemical expression of emmprin and morphometric analysis in adenoid cystic carcinoma / 
PY  - 2014///
CY  - Cairo : 
PB  - Hebatollah Khaled Mohamed Rizk , 
KW  - Adenoid cystic carcinoma
KW  - EMMPRIN
KW  - Morphometric analysis
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology; Issued also as CD
N2  - Adenoid cystic carcinoma (ACC) is one of the most common malignant tumors of salivary glands that often presents a diagnostic and treatment challenge. Our study aimed at  understanding the biological behavior of this neoplasm through comparing the expression of  the recent invasion molecular marker; extracellular matrix metalloproteinase inducer (EMMPRIN), as well as the cellular morphometric parameters (cellular area "CA", nuclear area "NA" and nuclear / cytoplasmic ratio "N / C ratio") among the 3 main histologic subtypes of ACC. The EMMPRIN expression area percent, as well as the morphometric parameters (CA, NA and N / C ratio) were measured and calculated in a total of 30 ACC specimens, roughly classified into ten cases having a predominating cribriform pattern, ten with tubular pattern, and ten with a solid pattern. EMMPRIN immunostaining as well as the CA, NA, and N / C ratio increased from the tubular group to the cribriform group, until reaching their highest values in the solid group. However, the statistical results of the  morphometric analysis were non - significant. EMMPRIN expression seems to be related to the histopathological pattern of ACC, suggesting that it might help in the future grading of this salivary gland malignancy
ER  -